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A fatal inheritance : how a family misfortune revealed a deadly medical mystery / Lawrence Ingrassia.

"Weaving his own moving family story with this sweeping history of cancer research, Lawrence Ingrassia delivers an intimate, gripping tale that sits at the intersection of memoir and medical thriller"-- Provided by publisher.
"Ingrassia lost his mother, two sisters, brother, and nephew to cancer―different cancers developing at different points throughout their lives. And while highly unusual, his family is not the only one to wonder whether their heartbreak is the result of unbelievable bad luck, or if there might be another explanation.  Through meticulous research and riveting storytelling, Ingrassia takes us from the 1960s―when Dr. Frederick Pei Li and Dr. Joseph Fraumeni Jr. first met, not yet knowing that they would help make a groundbreaking discovery that would affect cancer patients for decades to come―to present day, as Ingrassia and countless others continue to unpack and build upon Li and Fraumeni’s initial discoveries, and to understand what this means for their families.  In the face of seemingly unbearable loss, Ingrassia holds onto hope. He urges us to “fight like Charlie,” his nephew who battled cancer his entire life starting with a rare tumor in his cheek at the age of two―and to look toward the future, as gene sequencing, screening protocols, CRISPR gene editing, and other developing technologies may continue to extend lifespans and perhaps, one day, even offer cures."--Inside dust jacket

Record details

  • ISBN: 9781250837226
  • ISBN: 1250837227
  • Physical Description: 306 pages, 8 unnumbered pages of plates : illustrations (some color), genealogical tables ; 25 cm
  • Edition: First edition.
  • Publisher: New York : Henry Holt and Company, 2024.

Content descriptions

Bibliography, etc. Note:
Includes bibliographical references and index.
Subject: p53 antioncogene > Popular works.
p53 antioncogene > Patients > United States > Popular works.
p53 antioncogene > Patients > United States > Biography.
Cancer > Genetic aspects > Research > History > Popular works.
Fraumeni, Joseph F.
Li, Frederick P.
Ingrassia, Lawrence.
Ingrassia, Lawrence > Family.
Genre: Autobiographies.

Available copies

  • 0 of 2 copies available at Berks County. (Show)
  • 0 of 1 copy available at RACC.


  • 2 current holds with 2 total copies.
Show Only Available Copies
Location Call Number / Copy Notes Barcode Shelving Location Circulation Modifier Status Due Date Courses
RACC New - RC268.44.P16 I54 2024 (Text) 33624024977272 New Checked Out 07/24/2024

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